Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis and Pharmacotherapy

Contents

List of contributors

Acknowledgements

Foreword

Section A: Bipolar depression: Clinical phenotype and course of illness

The history of bipolar disorders

The clinical diagnosis of bipolar depression

Course and outcome of bipolar disorder – focusing on depressive aspects

Suicide and bipolar disorder

Section B: Bipolar depression: Neurobiology

The genetic basis of bipolar disorder

Understanding the neurobiology of bipolar depression

Non-pharmacological treatments and chronobiological aspects of bipolar disorder: implications for novel therapeutics

Neuroimaging studies of bipolar depression: therapeutic implications

Section C: Acute and long-term treatment of bipolar disorder

Pharmacological treatment of acute bipolar depression

Pharmacological treatment of the maintenance phase of bipolar depression: focus on relapse prevention studies and the impact of design on generalizability

Non-pharmacological somatic treatments for bipolar depression

Potential novel treatments for bipolar depression

Section D: Treatment of bipolar disorder in special populations

Late-onset bipolar disorder

Treatment of childhood-onset bipolar disorder

Treatment of bipolar disorder during and after pregnancy

Conclusion

Index

The MDT-Series Milestones in Drug Therapy