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Advances in Clinical Chemistry and Laboratory Medicine

of: Harald Renz, Rudolf Tauber

Walter de Gruyter GmbH & Co.KG, 2012

ISBN: 9783110224641 , 163 Pages

Format: PDF, Read online

Copy protection: DRM

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Price: 124,95 EUR



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Advances in Clinical Chemistry and Laboratory Medicine


 

Preface

5

1 Plenary Articles

19

1.1 Proteomics strategies targeting biomarkers for cardiovascular disease

21

1.2 Influence of pre-examination aspects on result’s validity – are ISO 15189 requirements sufficient and clear?

27

1.3 Posttranslational modifications in tumor diagnosis

30

1.4 Chronic inflammatory disease: a result of complex gene-environment interaction

34

2 Symposium Articles

39

2.1 Component-array technology diagnostics: a step forward in the study of the sensitization profile of allergic patients

41

2.2 Pediatric metabolic syndrome: pathophysiology and molecular mechanisms

44

2.3 Urinary 8-hydroxydeoxyguanosine as a biomarker of microangiopathic complications in type 2 diabetic patients

48

2.4 Biological variation data: the need for appraisal of the evidence base

53

2.5 RecoveryELISA - a newly developed immunoassay for measurement of therapeutic antibodies and the target antigen during antibody therapy

56

2.6 Genotypic prediction of HIV-1 tropism from plasma and peripheral blood mononuclear cells in the clinical routine laboratory

60

2.7 Expression of a subset of microRNAs in clinically non-functioning pituitary adenomas correlates with tumor size

64

2.8 Serological markers of gastric pathology

68

2.9 BNP as a biomarker of cardiac impairment in neonates with congenital heart diseases

72

2.10 Are 25-hydroxyvitamin D assays fit for purpose?

76

2.11 Update on multiple sclerosis

79

2.12 Microalbuminuria and urinary retinol binding protein as markers of subtle renal injury in visceral leishmaniasis: sensitivity, specificity and predictive values of the immunoturbidimetric technique

83

2.13 Occult hepatitis B virus infection: diagnosis and significance

86

2.14 Unmet needs in chronic kidney disease testing

90

2.15 Towards a national chronic kidney disease testing program

93

2.16 Biochemistry and metabolism of vitamin D

96

2.17 Diagnostics of thalassemia

100

2.18 The specific roles of assessors during accreditation

103

2.19 Laboratory diagnosis of hereditary spherocytosis

106

2.20 Quantification of blood folate forms using stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry

109

2.21 Evaluation of the new Marburg cerebrospinal fluid model with human spondylopathies

113

2.22 E-learning experiences of national societies of clinical chemistry and laboratory medicine

117

2.23 The experience of Médecins Sans Frontières in laboratory medicine in resource-limited settings

120

2.24 Screening, identifying, and quantifying small molecules by hyphenated mass spectrometry in toxicology and drug monitoring – an update

126

2.25 Analytical quality in the Latin America area

129

2.26 Standardization in molecular diagnostics: definitions and uses of nucleic acid reference materials

134

2.27 Profiling of antiphospolipid antibodies – association with cerebrovascular events in APS

138

2.28 Plasma levels of soluble CD30 and CD40L in pediatric patients after liver transplantation

142

2.29 Diagnostic and prognostic value of presepsin (soluble CD14 subtype) in emergency patients with early sepsis using the new assay PATHFAST presepsin

146

2.30 Diagnostic workup of primary aldosteronism

152

2.31 What should the clinical laboratory and the toxicologist-pharmacologist offer the poisoned patient?

156

2.32 Novel aspects of von Willebrand factor – platelet glycoprotein IB interaction and signaling

160

2.33 Medical emergencies: what is the laboratory’s role?

161